Portsmouth Hospitals NHS Trust was caring for 58 patients with coronavirus in hospital as of Sunday, figures show.
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Across England there were 3,356 people in hospital with Covid as of September 10.
Nationally, the number of hospital patients with Covid-19 has increased by 43% in the last four weeks.
The figures also show that 26 new patients with Covid were admitted to hospital in Portsmouth Hospitals NHS Trust in the week to September 8.